types of thrombectomy devices

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Ultrasound There are three types of thrombectomy device: aspiration, fragmentation and rheolytic. This occurs both through aspiration of blood through the catheter and by mechanical destruction of erythrocytes.11 Furthermore, substantial hemolysis can be detrimental in patients with renal insufficiency because plasma free hemoglobin can incite renal tubular damage. PMT is particularly well suited for the treatment of thrombosed hemodialysis access grafts, and most commercially available devices have been approved by the U.S. Food and Drug Administration (FDA) for this application. Separator-assisted clot debulking and aspiration (neurovasculature) Or, he or she may advise surgery if your blood clot is causing severe tissue injury. Mechanistically, these thrombectomy recirculation devices fall within 2 categoriesrotational and hydrodynamic. Thirteen years later, this group published 10-year follow-up data from the same cohort 13). A blunt rotating cam was mounted on its tip and could be driven coaxially at speeds up to 100,000rpm. The capsule houses an impeller that is driven coaxially up to 150,000rpm by high air pressure (50-100 psi). Ann Surg. Epub 2008 Sep 5. Trellis thrombectomy system for the treatment of iliofemoral deep venous thrombosis. Bethesda, MD 20894, Web Policies Rotational thrombectomy devices use a high-speed rotating basket or impeller to fragment the thrombus. Aspiration Catheters tarkov hidden stashes woods; social work case notes; jquery ajax vs fetch performance; parks motor sales staff; high school newspaper article ideas; aqa a level sociology families and households revision notes Medrad/Possis Based on Product Type, the Thrombectomy Devices Market from 2017 to 2027 is primarily split into: Hydrodynamic Ultrasound Aspiration Mechanical Thrombectomy The report studies end-user. Rotating wire fragmentation basket macerates thrombus. Severe anemia is a relative contraindication to PMT because substantial intraprocedural blood loss can be caused by these devices. The catheters are 7F and work over 0.014-inch guidewires. Before you agree to the test or the procedure make sure you know: The reason you are having the test or procedure, What results to expect and what they mean, The risks and benefits of the test or procedure, What the possible side effects or complications are, When and where you are to have the test or procedure, Who will do the test or procedure and what that persons qualifications are, What would happen if you did not have the test or procedure, Any alternative tests or procedures to think about, Who to call after the test or procedure if you have questions or problems, How much will you have to pay for the test or procedure. The Diver CE Clot Extraction Catheter and Export AP aspiration catheters (Medtronic, Minneapolis, Minn.) and the Fetch Aspiration Catheter (Medrad, Warrendale, Pa.) are similar devices. Int J Stroke 2017;12:896905.doi:10.1177/1747493017701147, Yamasaki K, Haruyama N, Taniguchi M, et al. The ReVene mechanical thrombectomy catheter is specifically designed to remove large, mixed-morphology blood clots commonly found with venous thromboembolism (VTE). 17) reported >50% thrombus extraction in 59% of patients treated with these devices and symptomatic improvement in 82%. The concurrent rinsing and aspiration is said to promote reperfusion. Covidien Sinusoidal vortex wire rotates and macerates thrombus. Global Thrombectomy Devices Market by Type (Automated, Manual), By Application (Peripheral, Coronary, Neural) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030. Normally, blood flows freely through your blood vessels, arteries, and veins. is, Although it no longer has a significant role, the Trac-Wright catheter (formerly known as the. Call your healthcare provider right away if you have any of the following: Weakness, pain, or numbness in the surgery area. Product . These shortcomings have driven the evolution of percutaneous mechanical thrombectomy (PMT). Direct contact mechanical fragmentation Technical concerns related to the use of all PMT devices highlight relative contraindications and should be considered in all applications before use. Blood clots in the brain can cause ischemic strokes. A neurovascular extension catheter is a newer approach that provides greater aspiration power to the small, distal vessels. Global Thrombectomy Devices Market is valued at approximately USD XX billion in 2021 and is anticipated to grow with a healthy growth rate of more than XX % over the forecast period 2022-2028. 2001; 12: 179185. This can block the blood flow. In its simplest form, percutaneous venous thrombectomy can be accomplished through large bore sheaths, but this approach is cumbersome and infrequently results in complete thrombus extraction 15). N Engl J Med 2015;372:228595.doi:10.1056/NEJMoa1415061, Jovin TG , Chamorro A , Cobo E , et al. To understand key trends, Download Sample Are there different types of thrombectomy? Advanced imaging is necessary in this group, however, if patients present beyond 6 hours from time last known well. In some cases, it may also be needed for a blood clot in an organ or other part of the body. Spectranetics 2008 Dec;29(24):3002-10. doi: 10.1093/eurheartj/ehn389. The following categories were introduced by Sharafuddin and Hicks12 and still provide an orderly framework to review commonly used devices in current clinical practice: Direct contact mechanical fragmentation. In 1994, Gulba et al 35) compared systemic thrombolysis and surgical embolectomy. The few absolute contraindications for the use of PMT are not application specific. The worldwide market for Thrombectomy Devices is expected to grow at a CAGR of roughly 5.1% over the next five years, will reach 1400 million US$ in 2023, from 1040 million US$ in 2017, according to a new study. Thrombectomy Devices Market Research Report, Types, Technology, Application and Region Forecast to 2026 - Boston Scientific, Medtronic, Teleflex Incorporated, Penumbra 03-09-2020 10:54 PM CET . The competitive landscape covers a Business Overview, Financials, Products and Strategies, and Recent Developments. In 1984, Plate et al in Sweden compared conventional anticoagulation with surgical venous thrombectomy and temporary arteriovenous fistula in patients with acute iliofemoral DVT 12). Merci Retrievers With the . J Am Coll Cardiol. The catheters are 7F and work over 0.014-inch guidewires. As device design continues to evolve, potential indications for PMT also expand. Click here. Acute pulmonary embolectomy: a contemporary approach. Each modality has benefits and shortcomings. A guide catheter with a gentle multipurpose curve is passed through an antegrade sheath, and the thrombus is crossed with a guidewire. Your arteries carry blood with oxygen and nutrients to your body. European Stroke Organisation (ESO) European Society for Minimally Invasive Neurological Therapy (ESMINT) Guidelines on Mechanical Thrombectomy in Acute Ischemic Stroke. The final category of device uses either direct or indirect ultrasound, laser, or . Circulation. Literature documenting efficacy in native arterial and bypass graft occlusion. There seem to be as many classification schemes as there are devices. Due to these technological advancements, the mechanical thrombectomy device segment is expected to be the largest segment, and witness to show significant growth over the forecast period. The growing geriatric population is leading in driving this market. You should stop smoking. They may include other medicines that stop the clot from getting bigger. However, despite continued innovation, no ideal device exists. In the United States, 3 classes of mechanical thrombectomy devices have been cleared by the Food and Drug Administration: coil retrievers in 2004, aspiration devices in 2008, and stent retrievers in 2012. The operation is advised for individuals who have had an acute ischemic stroke caused by a major arterial obstruction in the brain's anterior circulation. Mechanical thrombectomy in acute ischemic stroke: consensus statement by ESO-Karolinska stroke update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. Home - Thrombectomy Devices Market Type. Frisoli JK, Sze D. Mechanical thrombectomy for the treatment of lower extremity deep vein thrombosis. The report offers the value (in USD million) for the above segments. A multicenter randomized controlled trial of endovascular therapy following imaging evaluation for ischemic stroke (DEFUSE 3). Thrombectomy Devices Market Research With Terumo Corporation, Medtronic, Johnson & Johnson, Boston Scientific Corporation Size 2022 - Development, Potential Opportunities and Worldwide Study to 2028 . Vascular Solutions First, the doctor will find out the kind of stroke and where the clot is located. Thrombectomy Devices Market" By Types (Automated Thrombectomy Devices, Manual Thrombectomy Devices), Applications (Peripheral, Coronary, Neural), Regions and Forecast to 2028.The global Thrombectomy Devices market size is projected to reach multi million by 2028, in comparison to 2022, with unexpected CAGR during the forecast period, the Thrombectomy Devices Market Report Contains 107 pages . Endovascular therapy for ischemic stroke with perfusion-imaging selection. In February 2022, Cernuous, part of Johnson & Johnson Medical Devices Companies, launched EMBOGUARD, a next-generation balloon guide catheter to be used in endovascular procedures, including those for patients with acute ischemic stroke. At minimum, before pursuing PMT, the patient must be able to tolerate an endovascular procedure and contrast medium. Rheolytic thrombectomy with percutaneous coronary intervention for infarct size reduction in acute myocardial infarction: 30-day results from a multicenter randomized study. Feeling afraid or anxious can make it even harder to think clearly. The ANGIOJET Ultra Thrombectomy System is a mechanical thrombectomy device for PCI patients with large thrombus burden and the ONLY FDA-approved mechanical thrombectomy device for removal of thrombus in coronary arteries. Key market players are also involved in marketing strategies like a merger, acquisitions, etc in the segment tracked to gain a competitive edge in the region. 1.1 Study Assumptions and Market Definition, 4.2.1 Growing Geriatric Population Leading to Increase in CVDs Related Patients, 4.2.2 Technological Advancements in Medical Devices Used for Capturing Blood Clots, 4.2.3 Increased Awareness Regarding Early Diagnosis of Diseases, 4.3.2 High Cost and Difficultly Use of Devices for Complex Morphologies, 4.4.2 Bargaining Power of Buyers/Consumers, 6.1.7 Koninklijke Philips NV (Spectranetics), 7. By submitting, you confirm that you agree to Pullback thrombectomy and trapping Mechanical thrombectomy devices seek to. North America holds highest share in 2021. is the prototype pullback thrombectomy device and was introduced in 1969. No clinical data with this device are available. 2006 Jul;18 Suppl C:C24-7. Journal of NeuroInterventional Surgery Published Online First: 26 February 2019. doi: 10.1136/neurintsurg-2018-014569 https://jnis.bmj.com/content/early/2019/02/28/neurintsurg-2018-014569, Berkhemer OA , Fransen PS , Beumer D , et al. Plate G, Einarsson E, Ohlin P, et al. The Anaconda advanced thrombectomy system (Biomed) is an aspiration catheter system that comprises a delivery catheter and a novel funnel-shaped aspiration catheter which can expand to fit the size of the vessel it is deployed in ().The funnel shape is achieved by a stent mounted at and covered by the distal end of the . Kidney Int. Company Without blood and the oxygen it carries, that part of the brain starts to die. 1987; 1: 529533. Given the wide spectrum of PMT devices and their mechanism of action, clinical indications for their use are varied. ev3 The current iteration of the ATD is the Helix ClotBuster Mechanical Thrombectomy Device (ev3, Plymouth, Minn.) (Fig. A typical surgical thrombectomy may go like this: An IV will be put in your arm or hand before the procedure starts. Your healthcare provider will likely advise you to get back on your feet soon after the treatment. Although promising, experience with this type of apparatus is limited and there are few published reports documenting its usefulness in patients with acute DVT. The concurrent rinsing and aspiration is said to promote reperfusion. De Luca G, Dudek D, Sardella G, Marino P, Chevalier B, Zijlstra F. Eur Heart J. Dec 23, 2015 | Posted by admin in INTERVENTIONAL RADIOLOGY | Comments Off on Thrombectomy Devices. All PMT devices engage thrombus, fragment it, and most dispose of the effluent. Surgical venous thrombectomy is performed through a groin incision. Patency after iliofemoral and iliocaval venous thrombectomy. our privacy policy, By submitting, you confirm that you agree to our privacy Detailed Insights On Top Key Players of Thrombectomy Devices Market Report: Penumbra, Inc. Argon Medical Devices, Inc. Johnson and Johnson Terumo Corporation Medtronic plc Edwards Lifesciences Corporation Boston Scientific Corporation Spectranetics Corporation Teleflex Incorporated Patent femoropopliteal veins with competent valves were observed in 52% of the thrombectomy group and 26% of the anticoagulated group. The effects of coronavirus on the health of patients have increased cases of respiratory failures resulting in deaths. Careful monitoring during the procedure . Acolysis Ultrasound Thrombolysis System Examples of hydrodynamic recirculation devices include the AngioJet (Possis), the Hydrolyzer (Cordis), and the Oasis Thrombectomy System (Boston Scientific Corporation). Aklog L, Williams CS, Byrne JG, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. All responses are confidential. This product has the longest stent retriever in the phenoxy product portfolio. You might find it helpful to talk to a doctor who specializes in blood vessel problems. For peripheral applications, it is available in both 65- and 135-cm lengths. customized per your requirements. N Engl J Med 2018;378:1121.doi:10.1056/NEJMoa1706442, Albers GW , Lansberg MG , Kemp S , et al. The doctor will do a type of X-ray called a CT scan of the brain. Unable to load your collection due to an error, Unable to load your delegates due to an error. And with less damage to brain tissue, people are more likely to recover from a stroke. Penumbra's CAT family of catheters is engineered to be robust, trackable, atraumatic, and well suited to the peripheral anatomy where clots can form in long segments. Thrombectomy with temporary arteriovenous fistula: the treatment of choice in acute iliofemoral venous thrombosis. Some manufacturers (e.g., AngioJet) have obtained FDA approval for use of PMT devices in native coronary arteries, coronary bypass grafts, and all infrainguinal arteries of the lower limbs. Straub Medical Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. Catheter-directed thrombolysis (CDT) has advantages over surgical thrombectomy in the treatment of venous or arterial thrombosis. Straub Rotarex Catheter A thrombectomy is the removal of a thrombus and an embolectomy is the removal of an embolus. The current iteration of the ATD is the Helix ClotBuster Mechanical Thrombectomy Device (ev3, Plymouth, Minn.) (Fig. Although the ATD has gained acceptance in multiple clinical applications, its poor steerability and the tendency of the rotating cable to break when activated over acute angles are limitations. Therefore, due to the favorable reimbursement scenario for medical devices and aforementioned factors, the market is estimated to grow consistently in the North American region. To understand geography trends, Download Sample At Another Johns Hopkins Member Hospital: Percutaneous Transcatheter: Treatment of Deep Venous Thrombosis (DVT), DVT Prevention: Intermittent Pneumatic Compression Devices. Percutaneous mechanical retrieval of venous thrombi is a logical extension of open surgical thrombectomy, offering the potential advantage of rapid clearance of thrombus from occluded venous segments 14). Juhan C, Cornillon B, Tobiana F, et al. and transmitted securely. Negative pressure at the catheter tip draws adjacent thrombus into the end hole of the capsule, where it becomes fragmented by the rotating blades. 1970; 171: 923938. Lytic therapy was successful in 73% of patients whereas surgical treatment was successful in 85% of patients. 2004; 77: 819823. Combining these 2 treatment modalities offers the best opportunity for rapid clearance of thrombus, thereby decreasing the duration and dose of thrombolytic agent. Edwards Lifesciences Percutaneous mechanical thrombectomy procedures remove thrombus without thrombolytic drugs and thus may be a preferable treatment approach for these patients. Finally, embolization of thrombus fragment is better tolerated in the pulmonary arterial circulation than in a systemic arterial bed. The report offers the value (in USD million) for the above segments. Both rheolytic and aspiration devices have been unsuccessful to some degree in clinical trials; fragmentation thrombectomy is therefore the most commonly used technique. Summary. A blood clot can lead to many possible problems, such as: Swelling, pain, numbness, or tingling in an arm or leg, Blood clot moving to the lung that causes breathing trouble and risk of death (pulmonary embolism). (adsbygoogle = window.adsbygoogle || []).push({}); (adsbygoogle = window.adsbygoogle || []).push({ Vascular Solutions This study 36) has been criticized for a bias toward treating more severely ill patients with thrombolytics than with surgical embolectomy. Trellis Peripheral Infusion System J Invasive Cardiol. The thrombectomy devices market is expected to register a CAGR of 5% over the forecast period (2022-2027). 3.1 Products Development Trends of Different Types 3.2 Commercial Products Types of Major Venders 3.3 Competitive Landscape Analysis of Different Types 3.4 Market Size of Thrombectomy Devices by Major Types 3.4.1 Market Size and Growth Rate of Automated Devices The following categories were introduced by Sharafuddin and Hicks12 and still provide an orderly framework to review commonly used devices in current clinical practice: e7-1). Strategies, such as thrombectomy devices, to help reduce thrombus burden and prevent distal embolisation have been proposed to increase microvascular flow and improve outcomes. During the procedure, the doctor moves the catheter through the blood vessel into the brain. This will prevent pain and make you sleep during the surgery. Ligation of the inferior vena cava can prevent embolic events 6). The development of balloon thrombectomy catheters by Fogarty in the 1960s facilitated the procedure 4). Report scope can be Ultrasound-accelerated thrombolysis For another instance, in 2022 an article published in the National Library of Medicine reported that in the United States, about610,000 peopledie of heart disease every year. Venous thrombectomy for iliofemoral vein thrombosis10-year results of a prospective randomized study. Then a thin-walled wide-lumen catheter with a nontapered tip is advanced over the wire until it engages the thrombus. Stryker, Boston Scientific Corporation, Medtronic PLC, Terumo Corporation, Koninklijke Philips NV (Spectranetics) are the major companies operating in Global Thrombectomy Devices Market. The area may be numbed with a local anesthesia. 6 products CTO Crossing Devices 43 products Dialysis Catheters 81 products Disposable Transducers 10 products Embolic Protection Devices 8 products Endovenous Ablation 26 products FFR Technologies 5 products Fiber and Particulate Prevention Products 3 products Flow Diverters 3 products Fluid Delivery Sets 3 products Hemodialysis Flow Measurement The presence of coronary thrombus is often not appreciated on coronary angiography; however, simultaneous use of angioscopy or intravascular ultrasound increases the detection of thrombus. This can help limit damage to the brain. All surgery has risks. The final category of device uses either direct or indirect ultrasound, laser, or . The thrombectomy market is fragmented in nature due to the presence of several companies operating globally as well as regionally. Pulmonary embolism. In the last decade, there has been an explosion in neuroendovascular medical device innovation. Mechanical Thrombectomy/Thrombolysis Because thrombus is usually confined to the synthetic graft, the device may only have to be activated within the access, eliminating any potential endothelial damage. Intravenous (IV) thrombolysis plus mechanical thrombectomy is recommended for patients with large vessel occlusion-related ischemic stroke. Thrombectomy can remove the clot and help blood to flow normally again. However, if thrombus extends into the native veins, the thrombus can be removed with the same device. This consideration may be important when choosing the appropriate device in a native vessel or conduit. The catheter is also used to remove the clot. Make sure to keep all of your follow-up appointments. It represents a modified 7F version of the ATD and is reportedly more tolerant of acute angles. Examples of this type are the Amplatz thrombectomy device (Microvena), the Arrow-Trerotola percutaneous thrombolytic device (Arrow), and the Cragg-Castaneda thrombolytic brush (Microtherapeutics). Nanakramguda Rd, Financial District, Gachibowli. During a surgical thrombectomy, a surgeon makes an incision into a blood vessel. The market report also covers the estimated market sizes and trends for 17 countries across major regions globally. Hydrodynamic, or rheolytic, recirculation devices are based on the Venturi effect, created by high-speed saline jets directed retrograde. Risks include bleeding where the catheter was put in and a tear or sudden closure of a blood vessel. Today, positive pressure ventilation or the Valsalva maneuver is the preferred method of preventing distal embolization. Fogarty Graft Thrombectomy Catheter Besides, postponement in treatments using mechanical thrombectomy due to infection control measures has as well negatively impacted the market prospects. In some cases, a balloon or other device may be put in the blood vessel to help keep it open. Payment Failed. This occurs both through aspiration of blood through the catheter and by mechanical destruction of erythrocytes. Mechanical thrombectomy is type of minimally-invasive procedure in which an interventional radiologist uses specialized equipment to remove a clot from a patient's artery. The thrombectomy devices market is segmented by Product Type (Aspiration Thrombectomy Devices, Mechanical Thrombectomy Devices, Ultrasonic Thrombectomy Devices, Other Product Types), Applications (Cardiovascular Thrombectomy, Neurovascular Thrombectomy, Peripheral Vascular Thrombectomy), End-User (Hospitals/Clinics, Ambulatory Centers, Other End-Users), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). 13,14 As this embolisation occurs predominantly at the time of the initial balloon or stent inflation, using a thrombectomy device to reduce thrombus burden before . Rinspirator Thrombus Removal System Potential complications such as tolerance for endothelial injury, embolization, and hemolysis must also be weighed. They are used to remove blood clots from a main cerebral artery to restore blood flow after acute ischaemic stroke. A fashioned tip with a sloped extraction lumen protects the vessel wall during extraction. The Bacchus Trellis (Bacchus Vascular) is a relatively recent device, consisting of a catheter with proximal and distal occlusion balloons and a sheath designed to aspirate contents between the balloons. Various strategies have been used to restore patency of thrombosed veins, including open surgical thrombectomy, pharmacological thrombolysis, and percutaneous mechanical thrombectomy. The thrombus is broken down to small particles of which 98.8% to 99.2% are less than 13 m. A and B, The Boston Scientific Rotablator, which functions as rotational atherectomy. An official website of the United States government. The thrombus is usually acute and small in volume. Mechanical thrombectomy plus best medical management (including IV thrombolysis when indicated) is recommended for patients 80 years with large vessel occlusion-related acute ischemic stroke presenting within 6 hours of symptom onset. In some cases, a balloon attached to a thin tube (catheter) will be used in the blood vessel to remove any part of the clot that remains. The fragmented thrombus is then expelled radially through two side holes, and cleaved particles are repeatedly reaspirated, further macerating the thrombus. For example, like other endovascular procedures, PMT is contraindicated in infected vascular access and in arterial occlusion of a nonviable limb. However, with a rise in the burden of ischemic strokes across the globe, a novel treatment option known as mechanical thrombectomy has been made available by medical device companies. They can be of various types, such as aspiration thrombectomy devices, ultrasonic thrombectomy devices, mechanical thrombectomy devices, etc. N Engl J Med 2015;372:1120.doi:10.1056/NEJMoa1411587, Campbell BC , Mitchell PJ , Kleinig TJ , et al. The dye lets the doctor see a picture of the blood vessel on a video screen during the procedure. Fogarty TJ, Krippaehne WW. government site. More recently, Aklog et al 37) and Yalamanchili et al 38) have demonstrated that open pulmonary embolectomy can be performed in patients with minimal mortality and morbidity. For these reasons, proper indications of each particular device should be based on the manufacturers recommendations. Although successful as a salvage technique, results are unpredictable, especially with mature clot, often because of the inability to free thrombus from intrinsic and surrounding fibrosis. The Amplatz Thrombectomy Device (ATD; Microvena, White Bear Lake, Minn.) consists of a 6F or 8F catheter with a 1-cm long metallic capsule at its end. The Ultrasonic Thrombectomy Devices segment is anticipated to be the fastest-growing market. "Sorry! Literature documenting efficacy in native arterial and bypass graft occlusion,1 deep venous thrombosis,2 pulmonary embolism,3 and transjugular intrahepatic portocaval shunt (TIPS)4 and portal vein thrombosis5 is mounting. A blunt rotating cam was mounted on its tip and could be driven coaxially at speeds up to 100,000rpm. Major scientific advances have been made since the publication of the 2014/2015 consensus statement by the European Stroke Organisation (ESO)-Karolinska Stroke Update and the 2016 European Recommendations on Organisation of Interventional Care in Acute Stroke (EROICAS) 27), notably in the treatment of patients in late time windows (6 to 24 hours after stroke) 28). Iliocaval thrombosis8 Once removed, blood supply is restored and the patient is monitored for improvement. 1984; 1: 867876. The Global Thrombectomy Devices Market market is studied from 2019 - 2027. All PMT devices engage thrombus, fragment it, and most dispose of the effluent. (Courtesy ev3, Plymouth, Minn.) There is also a risk that your blood clot will form again. Market Research on Global Thrombectomy Devices Market 2021 by Manufacturers, Regions, Type and Application, Forecast to 2026 having 101.00 pages and priced at USD 3,480.00 launched by MarketResearchReports.com The screw fragments the thrombus, extracting much of it into a sheath through rotational motion. The higher risk of thromboembolism among COVID-19 patients led to increased demand for thrombectomy procedures thereby boosting market revenue. The Trellis device, which combines a high concentration of thrombolytic medication with mechanical disruption of the clot, has been used with some success to rapidly remove thrombus in patients with DVT 19). 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types of thrombectomy devices